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The dynamics of the pre-mRNA splicing factor SF2/ASF in a living baby hamster kidney cell nucleus

Overview of the dynamics of nuclear speckles enriched in pre-mRNA splicing factors. Each speckle is highly dynamic along its periphery and factors are recruited from these sites to sites of active transcription.

From: Misteli, T., J.F. Cáceres, and D.L. Spector. 1997. The dynamics of a pre-mRNA splicing factor in living cells. Nature 387, 523-527.