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Visualizing Gene Expression in Living
Cells
Live cell visualization of a stably integrated genetic
locus (yellow/green) using the lac operator/repressor system
and yellow fluorescent protein. In the transcriptionally
active state the locus is decondensed and transcribes an RNA
that encodes for a cyan fluorescent protein fusion that is
targeted to cytoplasmic peroxisomes. Photo provided by Susan
M. Janicki
Tsukamoto, T., N. Hashiguchi, S.M. Janicki, T.
Tumbar, A.S. Belmont and D.L. Spector. 2000. Visualization of
gene activity in living cells. Nature Cell Biology 2: 871-878.
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